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Sleep-disordered breathing and post-stroke outcomes

Annals of Neurology Jun 08, 2019

Lisabeth LD, et al. - This research draws on data from the population-based Brain Attack Surveillance in Corpus Christi Project (2010-2015) to explore the connection between sleep-disordered breathing and stroke results and how it contributes to Mexican Americans' outcome disparities. For this investigation, participation in a sleep-disordered breathing study including a home sleep apnea test (ApneaLink Plus) was provided to 995 ischemic stroke patients (median age was 67 years). Connections between sleep-disordered breathing and outcomes were evaluated with regression models, adjusted for socio-demographics, pre-stroke function and cognition, health-risk behaviors, stroke severity, and vascular risk factors. At 90 days post-stroke, sleep-disordered breathing was linked to worse functional and cognitive function. For future studies of a sleep-disordered breathing treatment with stroke, these results are reasonable endpoints. Ethnic disparities in stroke outcomes may be decreased somewhat the if sleep-disordered breathing treatment is effective.

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