Shorter defibrillation interval promotes successful defibrillation and resuscitation outcomes
Resuscitation Sep 27, 2019
Roh YI, Jung WJ, Hwang SO, et al. - The rate of successful defibrillation using 1- vs 2-min defibrillation intervals was investigated. Researchers performed random assignment of 26 pigs to 1- or 2-min interval groups. Two minutes following induction of ventricular fibrillation (VF), they initiated basic life support with a 30:2 compression-to-ventilation ratio for 8 min. With an energy of 2 J/kg at 10 min after VF, they performed defibrillation which was repeated every 1 or 2 min according to randomization. Until the return of spontaneous circulation (ROSC) or until 20 min after VF induction, they performed advanced cardiac life support, including continuous chest compression with ventilation every 6 s and intravenous injection of 1 mg epinephrine every 3 min. Outcomes revealed superior defibrillation success and resuscitation outcomes when a 1-min defibrillation interval was used in animal models of cardiac arrest.
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