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Shorter antibiotic regimens impact the control efforts in high tuberculosis burden regions of taiwan

International Journal of Infectious Diseases Jun 01, 2020

Lin YJ, Lin HC, Yang TF, et al. - Researchers investigated population and economic level impacts of shorter regimen on tuberculosis (TB) control in high TB burden regions of Taiwan. The TB population dynamic model and cost-effectiveness analysis were combined with local data to simulate the disease burdens, effectiveness, and costs of hypothetical 4-month, 2-month, and 7-day regimens compared with the standard regimen. Per findings, shorter regimens have potential for averting incidence, mortality, and disability-adjusted life year, incremental cost-effectiveness ratio, and net monetary benefit. Regimen shortening is a significant contribution to effective control of TB. They support shorter regimens in global- and regional-scale TB control strategies, which would improve disease control, especially in settings with high rates of incidence and poor treatment outcomes.

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