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Short-term results of interventional therapy for infants (7–36 months old) with patent ductus arteriosus and moderate-to-severe pulmonary hypertension: A retrospective study

Journal of Cardiothoracic Surgery Apr 28, 2020

Shu Y, Guo Y, Wang X, et al. - Researchers investigated the short-term (6 months) results and interventional therapy experience for infants with patent ductus arteriosus (PDA), a common congenital heart disease, and moderate-to-severe pulmonary hypertension. They retrospectively analyzed clinical records, echocardiographic data, and angiocardiography data of 28 infants (age, 7–36 months) on whom interventional therapy was performed for PDA and moderate-to-severe pulmonary hypertension between December 2011 and January 2017 at their hospital. An Amplatzer occluder was used with local and deep sedation anesthesia under radiographic guidance to treat all infants. Growth was poor in infants with PDA and moderate-to-severe pulmonary hypertension. They identified trace residual shunts in two infants immediately after procedure; both had disappeared by 6 months after procedure. Outcomes revealed achievement of excellent immediate and short-term (6 months) results in these infants (age, 7–36 months) in correlation with providing interventional therapy with careful preoperative evaluations, strict operative procedures, and careful follow-up.

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