Alnawaiseh M, et al. – The impacts of exercise on the optic nerve and macular perfusion utilizing optical coherence tomography angiography was assessed in this study. Increased physical activity induced significant changes in optic nerve and macular perfusion, which were measured using split–spectrum amplitude–decorrelation angiography optical coherence tomography angiography. In studies that aim to assess optic nerve and macular perfusion using optical coherence tomography angiography, it ought to be strongly suggested that patients rest before imaging is performed and that data concerning systemic circulation including blood pressure and pulse is included in the assessment.