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Sexual transmission of Zika virus and other flaviviruses: A living systematic review

PLoS Medicine Aug 08, 2018

Counotte MJ, et al. - A systematic review and evidence synthesis was performed to define the epidemiology of sexually transmitted Zika virus (ZIKV), as well as assess if flaviviruses can be transmitted through sexual intercourse. For this investigation, researchers carried out a living (ie, continually updated) systematic review of evidence published up to April 15, 2018 about sexual transmission of ZIKV and other arthropod-borne flaviviruses in humans and other animals. It was noted that ZIKV was more likely transmitted from men to women than from women to men. No evidence of sexual transmission for any other arthropod-borne flaviviruses was found. Findings revealed that that the infectious period for sexual transmission of ZIKV was shorter than estimates from the earliest post-outbreak studies, which were based on reverse transcription PCR alone.

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