Sex is associated with the persistence of non‐optimal vaginal microbiota following treatment for bacterial vaginosis: A prospective cohort study
BJOG: An International Journal of Obstetrics and Gynaecology Aug 20, 2020
Ratten LK, Plummer EL, Murray GL, et al. - Via this prospective cohort study of 75 reproductive‐age women diagnosed with clinical bacterial vaginosis (BV), treated with first‐line antibiotics and followed for up to 6 months, researchers investigated the correlations between factors and sexual practices and the composition of the vaginal microbiome (VM) in these women. They performed analysis of self‐collected vaginal swabs and the questionnaires completed by the participants. Findings revealed a VM comprising of increased relative abundance of non‐optimal BV‐associated bacteria and decreased relative abundance of optimal, Lactobacillus species among women who reported ongoing sex with a regular sexual partner (RSP). A decreased relative abundance of Lactobacillus spp. was reported in correlation with a history of BV. An increased relative abundance of Gardnerella, Atopobium and Sneathia spp. was observed following sex with an RSP. Findings thereby suggest association of sex with an untreated RSP after BV treatment with a VM comprising of non‐optimal BV‐associated bacteria. They emphasize the necessity for inclusion of partner treatment in BV treatment approaches for achievement of a sustained optimal VM associated with improved health outcomes.
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