Cannatà A, Fabris E, Merlo M, et al. - In a large cohort of patients with dilated cardiomyopathy (DCM), researchers examined the long-term prognostic role of sex. For this investigation, they prospectively recruited 1,113 patients with DCM. A propensity score–matching analysis was conducted on a sample of 586 patients to investigate the impact of sex. All-cause mortality/heart transplantation (HTx)/ventricular assist device (VAD), cardiovascular mortality/HTx/VAD, sudden cardiac death or malignant ventricular arrhythmias were all evaluated by estimating univariable and multivariable Cox models and competing-risk analyses on both cohorts. The investigators found that the long-term outcomes of women affected by DCM may be more favorable compared with men. Thus, findings supported sex as a significant independent factor, especially for cardiovascular outcomes.