Moore K, et al. - Researchers investigated gender related disparities in the acute complications of cardiac implantable electronic devices (CIED), including permanent pacemakers, implantable cardioverter defibrillators, and cardiac resynchronization therapy devices, focusing on in-hospital or within 90 days of discharge complications in patients aged >18 years, undergoing a new permanent pacemaker, implantable cardioverter defibrillator, or cardiac resynchronization therapy implant. The impact of sex was assessed using multiple logistic regression. This investigation included 81,304 new CIED (61,658 permanent pacemakers, 12,097 implantable cardioverter defibrillators, 7,574 cardiac resynchronization therapy) implants (38% women). A CIED complication was seen in 8.5% of women and 8.0% of men. Excess rate of in-hospital pleural drainage and pericardial drainage were the main drivers of differences in CIED complication rates. A higher risk of acute CIED complications was observed among women, which can be minimized by attaining improvements in implant technique and technologies.