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Severe symptoms persist for up to one year after diagnosis of stage I-III lung cancer: An analysis of province-wide patient reported outcomes

Lung Cancer Mar 04, 2020

Hirpara DH, Gupta V, Davis LE, et al. - Given an association of lung cancer with the significant disease- and treatment-related morbidity, researchers here investigated symptom severity in the 12 months following diagnosis of lung cancer and sought for predictors of high symptom burden. They conducted a retrospective population-based cohort study including patients with stage I-III lung cancer diagnosed between 2007–2016, and who had symptom screening in the 12 months following diagnosis. They plotted the proportion of patients, who described severe symptoms (ESAS ≥ 7) in the year following diagnosis, over time. They reported 69,440 unique symptom assessments among 11,075 lung cancer patients. The most prevalent severe symptom was tiredness (47.3 %), followed by shortness of breath (39.4 %) and poor wellbeing (36.5 %) among all disease stages. Severe symptom reporting in the year following diagnosis was observed in correlation with disease stage, comorbidity burden, degree of socioeconomic marginalization, and female gender. Targeted supportive care interventions, including psychosocial support aimed at improving health-related quality of life, may benefit those at risk of experiencing high symptom burden.
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