da Costa PM, et al. - Protective effects on adenoma detection and colorectal cancer (CRC) development and survival have been reported as resulting from higher vitamin D (25[OH]D₃) serum levels, so researchers investigated the correlation between serum vitamin D levels and the presence and histological grading of colorectal adenomas in peri- and post-menopausal women in this retrospective cohort study. Between 2004 and 2015, 315 peri- and post-menopausal women had opportunistic colorectal and osteoporosis screening at the gynecology outpatient clinic of a tertiary medical center and they were included for this study. Data revealed that the association of 25(OH)D₃serum levels with colorectal lesions appeared to be limited to adenomatous lesions and was influenced by histological grading. For optimizing risk stratification in group-specific CRC screening protocols, vitamin D could be a valuable biomarker.