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Serum vitamin A, zinc and visual function in children with moderate to severe persistent asthma

Journal of Asthma Oct 19, 2019

Andino D, et al. - In this cross-sectional case–control study, researchers analyzed urban children with moderate–severe persistent asthma (n = 24), to determine the prevalence of vitamin A as well as zinc deficiency in conjunction with visual function in these patients. Pediatric asthma cases with well-controlled disease, with ages between 8–18 years, corrected vision of at least 20/25 in each eye, and with chronic use of a combination beta agonist-steroid inhaler were eligible for inclusion. Snellen visual acuity and Peli Robson contrast sensitivity evaluation were used to determine visual function. According to the findings, reduced levels of vitamin A and zinc were detected in children with chronic asthma, which may be associated with disease pathobiology, however, there was no proof of frank zinc or vitamin A deficiency. The asthmatic group displayed reduced contrast sensitivity, which seemed unrelated to serum vitamin A and/or zinc levels.
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