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Serum uric acid level and subclinical coronary atherosclerosis in asymptomatic individuals: An observational cohort study

Atherosclerosis Jul 25, 2019

Lim DH, et al. - Researchers examined asymptomatic individuals (n=6,431; mean age 53.6 ± 7.6 years; 72.9% men) to determine the impact of serum uric acid (SUA) concentrations on subclinical coronary atherosclerosis, as detected by coronary computed tomography angiography (CCTA). The participants had no prior history of coronary artery disease and willingly underwent laboratory tests and CCTA as a component of a general health checkup. Based on SUA levels, they stratified participants into quartiles. In order to determine the link between SUA levels and subclinical coronary atherosclerosis, the investigators used logistic regression analysis. Findings revealed that non-calcified plaques in asymptomatic individuals were independently predicted by a high SUA level, which indicated an increased cardiovascular risk.

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