Azem R, Daou R, Bassil E, et al. - Researchers utilized the Cleveland Clinic CKD registry to examine the links between magnesium levels, chronic kidney disease (CKD) progression, death, and cause-specific deaths among patients suffering from CKD. Overall 10,568 patients with estimated Glomerular Filtration Rate between 15 and 59 ml/min/1.73 m² in this range for at least of 3 months with a recorded magnesium level were selected. The participants were divided into 3 categories on the basis of these magnesium levels (≤ 1.7, 1.7–2.6 and > 2.6 mg/dl). Higher all-cause and non-cardiovascular non-malignancy mortality were reported in correlation with hypomagnesemia in patients with CKD stage 3 and 4. Higher all-cause mortality related to hypermagnesemia was also reported. Neither hypo nor hypermagnesemia was found to be related to a heightened risk of CKD progression.