• Profile
Close

Serum levels of protein carbonyl, a marker of oxidative stress, are associated with overhydration, sarcopenia and mortality in hemodialysis patients

BMC Nephrology Jul 23, 2020

Song YR, Kim JK, Lee HS, et al. - Given that raised oxidative stress in end-stage renal disease is considered as one of the essential mechanisms in the atherosclerosis and muscle wasting, but researches assessing the clinical value of oxidative stress via direct measurement of these markers as well as its link with volume status and sarcopenia are limited, so, researchers measured serum protein carbonyl levels as a biomarker of oxidative stress in stable hemodialysis (HD) patients studied in this follow-up cross-sectional analysis. They identified a correlation of serum protein carbonyl levels with serum levels of albumin, prealbumin and transferrin, hydration status and low handgrip strength. In multivariate analysis, independent determinants of all-cause death were: serum levels of protein carbonyl, albumin, prealbumin, overhydration and sarcopenia. Overall, findings revealed a significant correlation of serum protein carbonyl with overhydration, nutritional status as well as sarcopenia, and showed that serum protein carbonyl could serve as a novel predictor of death in patients receiving HD.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay