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Serum glycine levels are associated with cortical bone properties and fractures risk in men

Journal of Clinical Endocrinology and Metabolism Jul 28, 2021

Eriksson AL, Friedrich N, Karlsson MK, et al. - In the present study, the researchers sought to examine correlations for serum and urinary glycine levels with bone mineral density (BMD), bone microstructure and fracture risk in men. Serum glycine and BMD were measured at baseline (n = 965) and 5-year follow up (n = 546) in the population-based MrOS Sweden study (men, 69-81 years). Using high resolution peripheral quantitative computed tomography, cortical and trabecular bone parameters of the distal tibia were measured at follow-up. Serum and urinary glycine are indirectly correlated with femoral neck-BMD and cortical bone strength, and directly related to fracture risk in men.

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