Lin CH, Chang CK, Shih CW, et al. - A total of 62 patients with euthyroid Grave disease (GD) and 62 healthy control individuals were recruited in a case-control study to examine the modifications of mineral metabolism in patients with GD who attained euthyroidism. Significantly greater serum fibroblast growth factor 23 and phosphorus, and lower 25-hydroxyvitamin D (25(OH)D) and intact parathyroid hormone (iPTH) levels were observed in euthyroid GD patients vs the control group. Following adjustment for age, gender, calcium, iPTH, and 25(OH)D, serum FGF23 was significantly and negatively associated with phosphorus level in the euthyroid GD group. In GD patients, serum phosphorus and FGF23 levels continued to be higher, even when the euthyroid status had been maintained for a median of 1.6 years. Moreover, in euthyroid GD patients, serum FGF23 was negatively related to serum phosphorus.