Barbosa S, Khalfallah O, Forhan A, et al. - Given that the ability of cytokines to regulate brain functions has been shown in animal and human studies, researchers investigated if there exists a link of individual cytokines with specific behavioral dimensions in population-based pediatric samples. They analyzed 786 mother-child pairs taking part in the French national mother-child cohort EDEN, utilizing the data and biological samples. Findings revealed increased odds of problems in prosocial behavior, emotions, and peer relationships in relation to interleukin (IL)-6, IL-7, and IL-15, respectively. Experts found reduced odds of problems in one dimension in relation to eight cytokines: IL-8, IL-10, and IL-17A with emotional problems, Tumor Necrosis Factor-α with conduct problems, C-C motif chemokine Ligand (CCL)2 with hyperactivity/inattention, C-X-C motif chemokine Ligand 10 with peer problems, and CCL3 and IL-16 with abnormal prosocial behavior. Without suggesting causation, the identified links are supportive of the role of cytokines as a regulator of brain functions and behavior.