Walther CP, et al. - This study was designed to ascertain the link between serum albumin concentrations and incident end-stage renal disease (ESRD) independently of urine albumin-to-creatinine ratio (ACR). Researchers found that lower serum albumin concentration was related to higher risk of incident ESRD independently of baseline urine ACR, estimated glomerular filtration rate and other ESRD risk factors in community-dwelling US adults.