Kuettel D, Glinatsi D, Ostergaard M, et al. - The present study was conducted to examine the pattern and longitudinal correlations of inflammatory lesions detected by serial MRI and US about patient-reported flares in individuals with RA. A total of 80 RA individuals with baseline DAS28CRP < 3.2 and no swollen joints were measured at baseline and followed for 1 year. By MRI/US, Synovitis and tenosynovitis increased significantly at flare onset. The evidence showed that patient-reported flares were correlated with all MRI and US inflammatory markers, except for BME, which was only correlated with SJC28 and long-lasting flares > 14 days in univariate models. Patient-reported flares are associated with tenosynovitis by MRI and US. Patient-reported flares were associated with inflammation identified by serial MRI and US. They found differential patterns of inflammatory lesion evolution by serial imaging with early synovial and tenosynovial inflammation, followed by delayed-onset BME.