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Septoplasty with or without concurrent turbinate surgery vs non-surgical management for nasal obstruction in adults with a deviated septum: A pragmatic, randomized controlled trial

The Lancet Jul 31, 2019

van Egmond MMHT, et al. - Via an open, multicentre, pragmatic, randomized controlled trial in 16 secondary- and two tertiary referral hospitals in the Netherlands of 203 adults (aged ≥ 18 years) with nasal obstruction, a deviated septum, and an indication to have septoplasty done, the researchers evaluated the efficiency of septoplasty for nasal obstruction in adults with a deviated septum. Participants were allotted to receive either septoplasty with or without concurrent turbinate surgery (n = 102) or non-surgical management (n = 101). At 12 months, 189 participants were evaluated with the mean score of 72·2 and 63·9 on the Glasgow Health Status Inventory of patients assigned to septoplasty and for those assigned to non-surgical management, respectively. Septal abscess and septal perforation occurred, respectively, in one and two surgical patients. No side-effects of nasal medication were noted. Hence, for nasal obstruction in adults with a deviated septum, septoplasty was concluded to be more efficient in comparison with non-surgical management. Moreover, this impact was sustained up to 24 months of follow-up.
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