Hsu YC, et al. - Risk factors for septic acute kidney injury (AKI) were investigated and the link between initial serum lactate level and septic AKI was clarified in Emergency Departments (ED) patients. In this retrospective cohort study, conducted at a single tertiary referral medical center, researchers reviewed the medical records of all adult ED patients with measurement of serum lactate and creatinine between January 2012 and December 2016 were reviewed. They noted overwhelmingly higher mortality rate for patients with septic AKI. In ED septic patients, the comorbidities of liver disease, diabetes mellitus, and chronic kidney disease were associated with septic AKI and in combination with an elevated initial serum lactate level were predictive of AKI and further mortality.