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Sensory function and pain experience in arthritis, complex regional pain syndrome, fibromyalgia syndrome, and pain-free volunteers: A cross-sectional study

Clinical Journal of Pain Oct 12, 2019

Palmer S, Bailey J, Brown C, et al. - Researchers investigated the associations of the sensory function with pain in 3 common pain conditions (arthritis, Complex Regional Pain Syndrome [CRPS] and fibromyalgia syndrome [FMS]) and pain-free participants. Given the concomitance of sensory abnormalities with some types of chronic pain, they sought to perform their comparison across pain conditions via employing pragmatic Quantitative Sensory Testing (QST) methods. 143 participants (n = 37 pain-free, n = 34 arthritis, n = 36 CRPS, n = 36 FMS) were examined for hot and cold sensitivity, light touch threshold (LTT), two-point discrimination and pain threshold. As per outcomes, extensive sensory dysfunction was evident among people with FMS and CRPS. Sensory profiles of patients with arthritis were closer to those of pain-free participants. Findings suggest a possible utility of LTT for a clinically relevant and accessible assessment for CRPS. Significant correlations were observed between LTT and pain outcomes bilaterally in CRPS.
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