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Self-reported periodontitis and fecundability in a population of pregnancy planners

Human Reproduction Apr 12, 2021

Bond JC, Wise LA, Willis SK, et al. - Via performing a prospective cohort study of 2,764 female pregnancy planners residing in North America (March 2015–June 2020), researchers sought to determine if a history of periodontitis among women is linked with reduced fecundability. Women were eligible for participation if they had been attempting pregnancy for six or fewer menstrual cycles at enrollment and were not using fertility treatment. Proportional probabilities regression models were used to determine fecundability ratios (FRs) and 95% confidence intervals (CIs) for three different measures indicative of a history of periodontitis: ever diagnosed with periodontitis (N = 265), ever received treatment for periodontitis (N = 299), and ever had an adult tooth become loose on its own (N = 83). Findings overall suggest a possible correlation of a history of periodontitis, as assessed by three different self-reported measures, with reduced fecundability.

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