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Selective serotonin reuptake inhibitors may lead to improved cataract surgery outcomes in patients with amblyopia

Clinical Ophthalmology Aug 17, 2019

Xin KZ, et al. - In this retrospective chart review study, researchers assessed the impacts of selective serotonin reuptake inhibitor (SSRI)/serotonin norepinephrine reuptake inhibitor (SNRI) medications in combination with cataract surgery in treating amblyopia in adult patients. This investigation was carried out on patients who had undergone cataract surgery at the Johns Hopkins Hospital Wilmer Eye Institute. There were a total of 237 patients, 38 of whom were on SSRI/SNRI. In patients on SSRI/SNRI, the mean improvement in visual acuity (VA) after surgery was not significantly greater. Worse baseline VA is linked to a greater improvement in post-op VA but an adverse effect on the absolute post-op VA. Findings suggested that when treated with SSRI/SNRIs, patients with amblyopia undergoing cataract surgery can potentially have a greater visual improvement.
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