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Second primary cancers and survival in patients with gastric cancer: Association with prediagnosis lifestyles

European Journal of Cancer Prevention Apr 04, 2019

Morais S, et al. - Among 574 patients with gastric first primary cancer (FPC), researchers examined the link between prediagnosis lifestyles with the risk of second primary cancers (SPCs) and survival. They assessed smoking, alcohol and dietary habits in the year prior to FPC diagnosis. The estimated 10-year cumulative incidence for SPC was 5.2% and estimated 15-year cumulative mortality was 72.1%. For SPCs, they found a significantly higher hazard ratio (95% confidence interval) in patients reporting a higher consumption of red and processed meat vs the lowest third; and those with heavy alcohol intake vs never drinkers and excess weight vs normal weight had a significantly higher hazard ratio (95% confidence interval) for mortality; no other significant links were found based on prediagnosis lifestyle. They concluded that among gastric FPC survivors, the occurrence of an SPC and survival in the long term could be influenced by prediagnosis lifestyles.

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