Saliva cotinine concentrations in pregnant women who smoke and use nicotine patches
Addiction May 25, 2019
Claire R, et al. - Researchers investigated if nicotine replacement therapy (NRT) should be stopped among pregnant women using NRT to stop smoking if they relapse to smoking. They designed a controlled pre-post study stratified by intervention condition from the Study of Nicotine Patch in Pregnancy, a randomized, placebo-controlled trial including 268 pregnant women. Pregnant smokers who were assigned to use nicotine patches or placebo and relapsed to smoking and continued to use their patches were compared regarding changes in saliva cotinine from baseline to 2 weeks post-target quit date. Outcomes revealed no change in the nicotine concentration from baseline among women trying to stop smoking with the aid of a nicotine patch that smoked at 2-weeks after their target quit date. However, these women said they smoked fewer cigarettes and had reduced carbon monoxide concentrations.
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