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Safety and performance of biodegradable magnesium-based implants in children and adolescents

Injury Mar 24, 2021

Stürznickel J, Delsmann MM, Jungesblut OD, et al. - The present study was conducted to examine the safety and performance of these implants in children and adolescents. Researchers examined 89 patients treated with magnesium-based implants for fracture stabilization, osteotomy, and osteochondral refixation; 38 were treated by osteosynthesis; 18, osteotomy; and 33, osteochondral refixation. (the mean follow-up duration was 8.2 months [range, 1.5-30 months]). They further conducted clinical and radiographical follow-up examinations at 4-8 weeks and 3-6 months, respectively, to assess implant performance and osseous consolidation. The results indicate that in children and adolescents, magnesium-based implants result in good clinical outcomes when used for fracture stabilization, osteotomy, and osteochondral defect refixation. Future trials are required to further examine the significance of the transient appearance and temporal development of radiolucent zones in the growing skeleton as well as the long-term performance of these implants.

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