Safety and efficacy of hydrogen peroxide topical solution, 40% (w/w) in patients with seborrheic keratoses: Results from two identical, randomized, double-blind, placebo-controlled, phase 3 studies (A-101-SEBK-301/302)
Journal of the American Academy of Dermatology Jun 06, 2018
Baumann LS, et al. - Authors assessed the safety/effectiveness of 40% hydrogen peroxide topical solution (HP40) compared to vehicle (VEH) for the treatment of seborrheic keratoses (SKs) (A-101-SEBK). They included 937 patients with 4 SKs (≥1 lesion each on face and trunk/extremity) and randomized 1:1 to HP40 or VEH. Findings suggested that the application of HP40 was well tolerated. An association of application of HP40 with the resolution of seborrheic keratosis was seen. Experts noted that the Local skin reactions were largely mild and by day 106, they resolved.
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