Rovinski D, et al. - A systematic review and meta-analysis were conducted to examine the risk of thromboembolic events in postmenopausal women using non-oral estrogen compared to women using oral estrogen and control groups (women receiving placebo or non-users of hormone therapy {HT}) and to evaluate the thrombotic impact of estrogens alone vs combined estrogen-progestin therapy. In postmenopausal women, venous thromboembolism (VTE) risk was increased with no previous thromboembolic events using oral HT. Findings revealed that non-oral hormone therapy did not affect the risk of venous thromboembolism.