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Risk of suicide attempt in patients with recent diagnosis of mild cognitive impairment or dementia

JAMA Mar 31, 2021

Günak MM, Barnes DE, Yaffe K, et al. - In this propensity-matched cohort study involving 147,595 older adults (21,085 patients with mild cognitive impairment [MCI], 63,255 with dementia, and 63,255 in the propensity-matched comparison group), researchers sought to investigate the correlation between diagnoses of MCI and dementia and suicide attempt, as well as explore potential psychiatric moderators and assess whether the connection varies based on recency of diagnosis. Exploratory analyses showed that no psychiatric comorbidity moderated the link between MCI or dementia and suicide attempt. After adjusting for demographic characteristics and medical and psychiatric comorbidities, the risk of suicide attempt was higher in patients with recently diagnosed MCI and those with recently diagnosed dementia vs those without MCI or dementia. The authors discovered that older adults with recent MCI or dementia diagnoses were more likely to attempt suicide. Such findings indicate that involving supportive services at the time of or soon after diagnoses of MCI or dementia may help reduce the risk of suicide attempts.

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