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Risk of psychosis among refugees: A systematic review and meta-analysis

JAMA Psychiatry Nov 17, 2019

Brandt L, et al. - Researchers performed the first and most comprehensive systematic review and meta-analysis, to date, examining the incidence of nonaffective psychosis among refugees vs the native population and nonrefugee migrants in a host country. Searching PubMed, PsycINFO, and Embase databases, they identified 9 studies (0.2%) involving 540,000 refugees in Denmark, Sweden, Norway, and Canada for inclusion in the analyses. Outcomes revealed a higher relative risk of developing nonaffective psychoses among refugees vs the native population and nonrefugee migrants. In studies with a low risk of bias, refugees exhibited a statistically significant increase in the relative risk to 1.39 compared with nonrefugee migrants and to 2.41 compared with the native population; available evidence was limited to Western host countries only. Among refugees in Denmark, Sweden, Norway, and Canada, refugee experience seems to represent an independent risk factor in developing nonaffective psychosis. This suggests a requirement for psychiatric prevention strategies and outreach programs for this group.
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