Oh J, Jung KJ, Kim TG, et al. - This study’s findings demonstrate the burden of psychiatric diseases in individuals with psoriasis in Korea and imply that appropriate medical support for possible mental illness is warranted in Asian psoriatic individuals.

• Researchers performed a nationwide cohort study encompassing more than 1.6 million Koreans with a 12-year follow-up period.

• As per the findings, individuals were considered to be in the psoriasis cohort whether they had an incident diagnostic code for psoriasis and enrolled individuals were followed up until they developed any psychiatric disease.

• In adjusted models, the results showed that psoriasis individuals (n = 10,868) were at an 18% elevated risk for depression (hazard ratio [HR], 1.18; 95% confidence interval [CI], 1.09–1.26), 16% for anxiety disorders (HR, 1.16; 95% CI, 1.08–1.26), and 21% for somatoform disorders (HR, 1.21; 95% CI, 1.08–1.34) in comparison with the referent cohort (n = 1,620,055).

• Compared to individuals with mild disease, individuals with moderate-to-severe psoriasis had a higher risk of developing depression and somatoform disorders (depression, HR, 1.28; 95% CI, 1.07–1.54 vs HR, 1.17; 95% CI, 1.07–1.27; somatoform disorders, HR, 1.60; 95% CI, 1.26–2.03 vs HR, 1.13; 95% CI, 1.00–1.28).