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Risk of prematurity and infant morbidity and mortality by maternal fertility status and plurality

Journal of Assisted Reproduction and Genetics Oct 21, 2018

Luke B, et al. - Researchers assessed the risk of prematurity and infant mortality by maternal fertility status, and for in vitro fertilization (IVF) pregnancies, by oocyte source and embryo state combinations. They linked women in 14 states who had IVF-conceived live births during 2004–13 to their infant’s birth and death certificates. They selected a 10:1 sample of non-IVF births for comparison and categorized those with an indication of infertility treatment on the birth certificate as subfertile and all others as fertile. Findings revealed an association of prematurity with placental complications, diabetes and hypertension, subfertility and IVF groups, and in IVF pregnancies, donor oocytes and/or thawed embryos.

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