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Risk of childhood mortality associated with death of a mother in low-and-middle-income countries: A systematic review and meta-analysis

BMC Public Health Oct 16, 2019

Nguyen DTN, Hughes S, Egger S, et al. - Given a heightened risk of childhood mortality, particularly in low-and-middle-income countries, may be seen in correlation with the death of a mother at an early age of the child, researchers estimated the risk of childhood mortality at different age ranges from birth to 18 years in these settings in correlation with mother’s death. They identified 12 original studies from MEDLINE databases, EMBASE, and Global Health databases. These studies were population-based cohort and case-control studies published from 1980 to 2017 and provided 62 stratified risk estimates. In lower resource settings, a link was evident between the death of a mother and childhood mortality. The relative risk (RR) of dying within the first 1–6 months of the child’s life was estimated to be 35.5 for those whose mother died when they were ≤ 42 days vs those whose mother did not die; a decline in this risk to 2.8 was noted by 6–12 months. For children whose mother died when they were ≤ 1 year vs those whose mother lived, the subsequent RR of dying in that year was estimated to be 15.9. Overall, women are critically important in family outcomes and healthcare is significant for women during the intrapartum and postpartum days and during their child rearing years.
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