ElSheemy MS, et al. - The authors strived to identify the possible risk factors for UC and UTI following pediatric renal transplantation (Tx) and they determined the impact of these complications on the outcome. No marked link was noted between UC and UTI with increased graft loss or mortality. UC appeared to be substantially higher in children with cystoplasty. On the other hand, UTIs were notably higher in girls and children with urological causes of ESRD. The rate of graft loss or mortality was not influenced by the presence of UC, owing to its early detection and proper management.

Methods

• The enrolled candidates included 108 children who underwent living donor Tx between 2009 and 2015.
• During this study, extraperitoneal approach was used with stented tunneled extravesical procedure.

Results

• It was determined that the mean recipient age was 9.89 ± 3.46 years.
• The mean weight was 25.2 ± 10.43 kg.
• Seventy-three (67.6%) recipients were boys while 92 (85.2%) were related to donors.
• The presence of urological causes of ESRD were noted in 33 (30.6%) recipients (14 [13%] posterior urethral valve, 16 [14.8%] VUR, and 3 [2.8%] neurogenic bladder).
• Augmentation ileocystoplasty was performed in 9 (8.3%) patients.
• Mean follow-up was 39.3 ± 17.33 months.
• This study detected UC in 10 (9.3%) children (leakage 4 [3.7%], obstruction 3 [2.8%], and VUR 3 [2.8%]).
• On the other hand, UTIs were reported in 40 (37%) children.
• A prominently higher UC were unveiled in children with cystoplasty (44.4% vs 6.1%; P=.001), after logistic regression analysis.
• UTIs were discovered to be considerably higher in girls (51.4% vs 30.1%; P=.001) and in children with urological causes of ESRD (51.5% vs 30.7%; P=. 049).