Shao J, et al. - The predictive risk factors for the surgical site infection after open reduction internal fixation of ankle fractures were assessed for the first time in this study. Researchers identified body mass index (both continuous and dichotomous variables); American Society of Anesthesiologists ≥3; diabetes; alcohol; open fracture; subluxation/dislocation; incision cleanness grade 2–4; high-energy mechanism; chronic heart disease; history of allergy; and use of antibiotic prophylaxis as the significant increased risk factors with surgical site infection after open reduction and internal fixation of ankle fractures.