Possner M, Tseng SY, Alahdab F, et al. - Given increased risk for death, sudden cardiac death, and ventricular tachycardia (VT) in patients with repaired tetralogy of Fallot, researchers intended to afford an updated analysis of risk factors after significant changes in surgical as well as perioperative management, by performing this systematic review and meta-analysis based on the published literature. VT, cardiac mortality/VT, and all-cause mortality/VT were the endpoints, and 15 studies with 7,218 patients (average age 27.5 years) were included. Older age, older age at corrective surgery, previous palliative shunt, number of thoracotomies, longer QRS duration, and at least moderate right-ventricular dysfunction were all identified as risk factors for VT. Previous ventriculotomy, lower left-ventricular ejection fraction, and higher right-ventricular end diastolic volume were documented as additional risk factors for cardiac death/VT. An additional risk factor for all-cause death/VT was supraventricular tachycardia/atrial fibrillation. Overall, findings revealed the significance of preservation of biventricular systolic function on late results. A seemingly greater effect of ventricular function on outcomes, vs the severity of pulmonary regurgitation alone, was suggested in this patient population.