Cha SM, et al. - A retrospective case-control study was conducted to determine the diagnostic factors for atypical forearm fractures additional to atypical femur fractures. A complete enumeration survey for patients under the treatment of bisphosphonate (BP) was performed. Between March 2009 and February 2019, researchers distinguished 53 individuals that met the following inclusion criteria: a BP therapy history or ongoing administration of at least 1 year, presence of simple radiographs of bilateral femurs and forearms, and availability of complete medical records and radiological data. Individuals were categorized into two groups: those with any lesion of atypical fractures of ulna or radius, regardless of the displacement of at least one side extremity in simple radiographs (group 1, 20 patients); and those without any lesions of pathognomonic finding or fractures in either forearm in simple radiographs (group 2, 33 patients). This study’s findings demonstrate that atypical forearm fractures are probably more common than reported in the literature to date, and all forearm lesions were accompanied by preceding atypical femur fractures. The data exhibited that the period of BP administration had the main effect on the occurrence of atypical forearm fractures, especially whether more than 65 months. Also, It was demonstrated that prescription by multiple physicians was a prognosticating factor for forearms lesion additionally to atypical forearm fractures, nevertheless, a future evidence-based study is required to understand the impacts of cancer-related BP usage on the forearm.