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Risk factors and clinical features of paroxysmal sympathetic hyperactivity after spontaneous intracerebral hemorrhage

Autonomic Neuroscience: Basic and Clinical Feb 01, 2020

Li Z, Chen W, Zhu Y, et al. - Researchers used multivariate logistic regression analysis to assess the risk factors and clinical characteristics for paroxysmal sympathetic hyperactivity (PSH) after intracerebral hemorrhage (ICH). Patients with ICH were consecutively included from January 1, 2013, to April 1, 2018. In this observational study, there were 548 ICH patients involved and a total of 15 patients were identified with PSH. PSH development was correlated with the following in univariate analysis: prior hemorrhagic stroke, pupils abnormity, admission Glasgow Coma Scale (GCS) score, hematoma volume, liver function abnormity, neutrophil count and early tracheostomy. According to multivariate logistic regression analysis, a significantly raised risk of PSH was observed in patients with prior hemorrhagic stroke, admission GCS score, and early tracheostomy. Hyperthermia and hyperhidrosis were the most common symptoms of PSH. PSH is characterized by a cluster of symptoms and abnormal vital signs that can result in poor ICH outcomes.
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