Rheumatoid arthritis and mortality in end stage renal disease
Journal of Clinical Rheumatology Feb 26, 2020
Paudyal, S, Waller, JL, Oliver, A, et al. - This study was undertaken to investigate whether rheumatoid arthritis (RA) is a risk factor for cardiovascular disease (CVD) events, all-cause mortality and cardiovascular mortality in end-stage renal disease (ESRD). Researchers performed a cohort study including adult individuals with ESRD in the United States Renal Data System with RA and a 5% random sample of those without RA. They ascertained CVD events, all-cause mortality, and cardiovascular mortality in those with RA compared with those without RA using Cox Proportional Hazards modeling. A total of 2,824 individuals were recruited (407 with RA and 2,417 without RA individuals). The findings considered that clinicians should be aware that persons with RA who develop ESRD incur cardiac events sooner than the general population. Nevertheless, RA is not an independent risk factor for all-cause or cardiovascular mortality in ESRD.
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