Peters JB, et al. - Researchers conducted retrospective chart review and case studies in a reproductive endocrinology practice to report on two women in early menopause with alopecia and high mercury (Hg) levels which reversed with a decrease in toxic levels. Sudden circumscribed hair loss on the scalp was reported in a 43-year-old woman initially evaluated for early menopause. The case reported elevated Hg levels in blood tests and a diet high in tuna. Elimination of dietary tuna led to the reduction in the levels. Development of alopecia was also reported in another woman (39 years old) who was complaining of severe hot flashes, night sweats, and menstrual irregularity. Treatment with low testosterone was unsuccessful, high Hg levels were evident in blood tests and hair loss was observed simultaneously. A reversal of alopecia, along with a decrease in blood Hg levels were noted following the recommendation to alter diet, including fish intake. These two cases led researchers to recommend considering for measurement of Hg levels in women with alopecia.