Retrospective analysis of tacrolimus combined with Tripterygium wilfordii polyglycoside for treating idiopathic membranous nephropathy
BMC Nephrology Jul 25, 2018
Shang SL, et al. - In a retrospective case series, researchers evaluated the impacts of tacrolimus (TAC) combined with Tripterygium wilfordii polyglycoside (TWG) in treating idiopathic membranous nephropathy (IMN). They analyzed data from kidney-biopsy-proven IMN patients treated with TAC in the Chinese PLA General Hospital. Remission rate (complete remission and partial remission) was considered as the first efficacy evaluation index, and the secondary efficacy evaluation indices included relapse rate, proteinuria, serum albumin and estimated glomerular filtration rate (eGFR). Evaluation of adverse events was also carried out. Based on the findings, they concluded that TAC combined with TWG may be effective for treating IMN.
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