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Retronasal olfactory function in patients with smell loss but subjectively normal flavor perception

The Laryngoscope Sep 10, 2019

Liu DT, et al. - In patients with non-sinonasal smell loss and subjectively normal flavor perception, researchers compared orthonasal and retronasal olfactory function. The study sample consisted of 19 patients (mean age [range] 52.0 [8–83 years]) with self-reported olfactory impairment but subjective normal flavor perception. Using the Sniffin’ Sticks for orthonasal and the Candy Smell Test (CST) for retronasal function, the olfactory performance was evaluated. The current findings indicate that normal perception of subjective flavor in non-sinonasal smell loss patients is not confirmed by the outcomes of retronasal smell testing. The findings of orthonasal and retronasal smell testing in most of the patients examined yielded scores within the range of anosmia. These results indicate that an unconscious memory recall from previous experienced cross-modal sensory interactions may mediate part of the representation of retronasal smell within flavor perception. There has been no correlation between self-assessment of flavor perception and CST. Possible anatomical, histological and physiological variations will be the topic of future inquiries between groups of anosmic patients with and without noticing the reduction in flavor perception.
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