Shields CL, Srinivasan A, Lucio-Alvarez JA, et al. - Researchers conducted the study for exploring clinical features and long-term outcomes in patients with retinocytoma/retinoma. The records of patients with retinocytoma/retinoma over a 20-year period have been reviewed retrospectively to compare patient age at presentation (< 4 vs ≥ 4 years), tumor type, and tumor focality (unifocal vs multifocal). Retinocytoma was more common in older patients than retinoma, with fewer symptoms, a larger median basal diameter, greater thickness, and less frequently with additional retinoblastoma in either eye. The rate of retinocytoma/retinoma transformation into retinoblastoma increased from 2 to 10-20 years of age in the study cohort. Increased tumor thickness was the only factor that predicted transformation.