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Retinal venous pressure is decreased after anti-VEGF therapy in patients with retinal vein occlusion–related macular edema

Graefe's Archive for Clinical and Experimental Ophthalmology Jan 20, 2021

Kida T, Flammer J, Konieczka K, et al. - In this prospective study, researchers assessed changes in the retinal venous pressure (RVP) following intravitreal injection of anti-vascular endothelial growth factor (VEGF) agent to determine the impact on retinal vein occlusion (RVO)-related macular edema. Participants in the study were 26 patients with RVO-related macular edema (16 branch RVOs [BRVOs] and 10 central RVOs [CRVOs], age 72.5 ± 8.8 years) who visited the hospital. Treatment with anti-VEGF resulted in a substantial decrease in RVP, but RVP remained substantially higher than IOP. An increased RVP plays a decisive role in the production of macula edema, and it is beneficial to reduce it.

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