Harimoto A, Obata R, Yamamoto M, et al. - Researchers conducted this retrospective consecutive observational cohort study to examine retinal sensitivity of highly myopic eyes without choroidal neovascularisation (CNV) or patchy chorioretinal atrophy (PCA) and investigated its relationship with anatomical characteristics including melanin distribution at the retinal pigment epithelium (RPE), which was assessed with polarisation-sensitive optical coherence tomography (PS-OCT). Twenty-three highly myopic eyes (age, 66.6±12.3 years) were involved in this analysis. Reduced depolarisation at the RPE, as measured by PS-OCT and reflecting altered melanin pigmentation, was found to be independently associated with reduced retinal sensitivity in patients with early stages of myopic maculopathy without CNV or PCA.