Yu J, et al. - A case-control study is performed to assess and compare changes in retinal nerve fiber layer (RNFL) thickness in patients with the pseudoexfoliation syndrome (PXS) and healthy controls. These outcomes propose that it is vital to assess RNFL thickness and the optic nerve head through optical coherence tomography (OCT) in patients with PXS in order to ascertain early glaucomatous damage and start timely intervention prior to visual field loss.