Dallorto L, Lavia C, Jeannerot AL, et al. - Among 17 consecutive pituitary adenoma (PA) patients and 16 healthy individuals, researchers conducted this cross-sectional, retrospective study to analyze retinal vascular changes in the peripapillary and macular areas using optical coherence tomography angiography. To evaluate the presence of optic neuropathy (ON), all participants had a neuro-ophthalmological examination. In 16 eyes of nine PA patients, ON was found. According to retinal nerve fibre layer and ganglion cell complex thinning, optical coherence tomography angiography displayed a significant reduction in peripapillary vessel density and superficial macular vessel density in PA eyes with ON vs healthy eyes. It can provide additional insights into neurovascular coupling together with the absence of deep vascular complex alterations.