Baekgaard JS, et al. - Among 41 adult trauma patients, the feasibility of using a restrictive oxygen strategy in the initial phase after trauma to maintain normoxia, was assessed, as well as the incidence of 30-day mortality and/or major pulmonary complications. Researchers randomly assigned 21 patients to 24 hours of restrictive oxygen therapy (no supplemental oxygen if the arterial oxyhaemoglobin saturation (SpO₂) was at least 94%) and 20 patients to liberal oxygen therapy (intubated patients: FiO₂ 1.0 in the trauma bay, 0.8-1.0 elsewhere; spontaneously breathing patients: 15 L/min via a non-rebreather mask, n = 20). In the restrictive group, seven episodes of SpO₂ below 90% were reported, whereas, one episode was reported in the liberal group. In the restrictive group vs in the liberal group, 4/20 and 6/18 (33%) patients, respectively, suffered 30-day mortality and/or major in-hospital pulmonary complications. Overall, it was feasible to maintain normoxia using a restrictive oxygen strategy following trauma.